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Breast Cancer

Next to skin cancer, breast cancer is the most common form of cancer among women, affecting one woman out of every eight at some point in life. Breast cancer also occurs among men, although at a much lower rate. Symptoms include a lump or thickening in the breast; a clear, bloody, or yellow discharge from the nipple; and, only in rare instances, breast pain. Cancerous breast lumps are firm and do not shrink and expand with the menstrual cycle. While most lumps are not cancerous, any breast abnormality should be brought to the attention of a doctor.

Some of the major risk factors for breast cancer include age, family history, smoking, alcohol consumption, radiation exposure, and, in post-menopausal women, obesity. For women who do not smoke, however, the most important risk factor is exposure to the female hormone estrogen over the course of a woman's lifetime. Approximately 75 percent of all breast cancers are stimulated by estrogen. Higher levels of estrogen in the bloodstream are associated with recurrence, resistance to treatment, and mortality. These cancers are called estrogen-dependent. Lifetime estrogen exposure is highest if menstruation starts at an early age, a woman bears children either late in life or not at all, menopause occurs late, and she uses estrogen replacement therapy.

Breast cancer is classified according to a multistage system that measures tumor size, the amount of lymph-node involvement, and the absence or presence of metastases to other organs such as the bones, lungs, and liver. The main treatment is surgery. This ranges from lumpectomy, in which the lump itself is removed with a small amount of surrounding tissue, through more extensive operations to radical mastectomy, in which the breast, parts of the chest muscle, and armpit lymph nodes are removed. After surgery, radiation therapy or various forms of chemotherapy may be used.

One of the most useful treatments is hormonal therapy, including tamoxifen (Nolvadex). Estrogen interacts with an anticancer gene known as gene p53. This gene is a "molecular patrolman" that makes sure genetically defective cells do not multiply. Estrogen, however, promotes so much cellular growth within the breast that gene p53 cannot keep track of all the defective cells. Removing estrogen reduces the rate of cell growth so that this gene can do its job. Gene p53 is not alone in regulating cancer cells. Another gene, p21, stops the transformation of cells into a cancerous state even before they trigger the alarm for gene p53. Fortunately, isoflavones from both soy and kudzu activate p21.

There are herbs and formulas that offset the side effects of chemotherapy and radiation therapy, as well as providing other benefits. Always use herbal medicine as part of a medically directed overall treatment plan for breast cancer.

Supplements and herbs

  • Astragalus capsules. Take 500-1,000 mg 3 times daily.
    Stops spread of cancers that respond to gene p53.
    Do not use astragalus if you have a fever or a skin infection.
  • Cat's claw tincture. Take as directed on the label in 1/2 cup water with 1 tsp lemon juice.
    A potent immune stimulant.
    Do not use cat's claw if you have to take insulin for diabetes. Do not use it if you are pregnant or nursing. Do not give it to a child under age six.
  • Garlic enteric-coated tablets. Take at least 900 mg daily.
    Stops proliferation of estrogen-activated cancer cells, complementing tamoxifen.
    Garlic counteracts the effects of bifidus and lactobacillus cultures taken as digestive aids. Consult a doctor before using garlic on a regular basis if you are on an anticoagulant medication as warfarin (Coumadin). Discuss the use of garlic with your doctor before having any type of surgery.
  • Green tea catechin extract. Take 240 mg 3 times daily.
    Blocks estrogen receptors, reinforcing action of tamoxifen.
  • Kudzu tablets. Take 10 mg 3 times daily.
    Activates gene p21.
  • Lentinan intramuscular injection, given by health-care provider.
    Activates Iymphokine-activated killer (LAK) and natural killer (NK) immune system cells to fight cancer.
  • Maitake - Maitake-D. Take 2,000 mg 3 times daily, before meals.
    Stimulates the immune system. Slows tumor growth.
  • Milk thistle silymarin gel-caps. Take 120-320 mg capsules daily.
    Binds to estrogen receptor sites on cancer cells.
    Milk thistle may cause mild diarrhea. If this occurs, decrease the dose or stop taking it.
  • Mistletoe loranthus or mulberry mistletoe. Use only under professional supervision.
    Complements chemotherapy by preventing immune suppression.
  • Quercetin tablets. Take 125-250 mg 3 times daily, between meals.
    Accelerates cancer cell death in treatment for multi-medication-resistant cancer.
    Do not use quercetin if you are taking cyclosporine (Neoral, Sandimunne) or nifedipine (Adalat, Procardia).
  • Red wine catechins Resveratrol tablets. Take 125-250 mg 3 times daily.
    Stops cellular processes that cause tumor development and growth.
  • Soy isoflavone concentrate tablets. Take 3,000 mg daily.
    Blocks estrogen from cancer cells. Activates gene p21.
  • St. John's wort capsules. Take 300 mg 3 times daily.
    Prevents spread of cancer to tissues between chest wall and lungs.
    Do not use St John's wort if you are on prescription antidepressants or any medication that interacts with MAO inhibitors. Use it with caution during pregnancy. This herb may increase the chance of developing sun blisters if you are out in the sun for too long.
  • Turmeric curcumin tablets. Take 250-500 mg twice daily between meals.
    Activates p53; suppresses other genes that activate cancers.
  • Vitex capsule, tablet, or tincture. Use as directed on the label.
    May inhibit the growth of breast cancer cells.

HERBS TO AVOID - Women who have breast cancer should avoid the following herbs: cordyceps, dan shen, fennel, licorice, and peony.

What else you can do

  • Avoid accumulating body fat through exercise and by eating the right kind of dietary fat in appropriate quantities. This means you should not eat red meat, butter, and lard, especially if you have not yet entered menopause, as these fats can promote cancer development. Instead, you should eat omega-3 fatty acids, the kinds of fats that protect against cancer. Omega-3s are found in fish oils-eating two to three servings of salmon, tuna, sardines, or other coldwater fish a week, or taking fish oil capsules, can supply the omega-3 you need. Other healthy fats include olive oil and similar monosaturated fats.
  • Women who eat vegan diets, or diets that include no animal products at all, should consume plant oils on a daily basis. Laboratory research suggests that beta-sitosterol, a component of almost all vegetable fats, greatly reduces the growth of estrogen-stimulated breast cancer.
  • Eat fruits and vegetables that are rich in beta-carotene. On average, women with breast cancer tend to have lower levels of beta-carotene in their blood, although doctors cannot say whether this is a cause or a result of the disease. A small-scale study in Italy found that beta-carotene given with other, related carotene compounds increased the tumor-free period among women who had already had breast cancer. The safest and most effective way of maintaining healthy levels of beta-carotene is to consume three or more servings of dark-green, yellow, or orange vegetables and citrus fruits daily.
  • Eat broccoli. Of all the cruciferous (cabbage family) vegetables, broccoli appears to have the greatest cancer fighting potency. Broccoli contains sulphoraphane, a compound that helps the body begin to eliminate carcinogenic toxins in as little as ten days after it is included in the diet on a daily basis. It also keeps estrogen from binding to and stimulating the growth of breast cancer cells. Sulphoraphane survives both steaming and micro waving.
  • Avoid fried foods and charcoal-grilled meats. Studies indicate that daily consumption of fried foods can raise the lifetime risk of getting breast cancer from one in nine to two in nine, and that daily consumption of grilled meats can raise the risk to five in nine.
  • Do not binge on sweets and starches. Eating a lot of sweet or starchy food at once causes the body to release a massive amount of the hormone insulin, which seems to accelerate the growth of breast cancer cells. If you have diabetes, try to manage your diet so that you maintain healthy blood-sugar levels with the smallest amount of insulin possible.
  • Get a little sun. There is some evidence that vitamin D can help transform breast cancer cells into healthy cells. Vitamin D supplements are not necessary; all that is needed for the body to manufacture adequate amounts of vitamin D for fighting cancer is to expose your hands and  face to sunlight for twenty minutes each day. Do not use sunscreen during this twenty-minute period, since sun blocks screen out the kind of ultraviolet light that stimulates the natural production of the vitamin. The effectiveness of vitamin D in fighting cancer, in turn, depends on adequate supplies of vitamin C, which is best provided by daily servings of fruits and vegetables.
  • Make sure your diet includes fresh apples, cherries, grapes, plums, and all types of berries.
  • Take extra fiber daily. Fiber keeps toxic wastes from being absorbed into the bloodstream.
  • Eat onions and garlic, or take garlic supplements.
  • Relaxation techniques such as writing, meditation, yoga, or massage therapy can aid in battling breast cancer.
  • Hormonal therapy uses medications that act like estrogen within the body. They attach to cells at the same places estrogen does, but stimulate less cell growth. This gives genes p21 and p53 less work to do. Tamoxifen (Nolvadex) is a medication widely used after surgery for this purpose. However, while tamoxifen reduces the risk of breast cancer, it increases the risk of uterine cancer.
  • The hormone melatonin produces a hundredfold increase in the effectiveness of tamoxifen. Used by itself or with astragalus, it also increases the effectiveness and reduces the side effects of an immune-system component called interleukin-2 that is sometimes used in treatment.  Laboratory tests have found that selenium and magnesium reduce the incidence of new breast cancers when taken with adequate dietary supplies of vitamins A, C, and E. Vitamin E is especially important for the anticancer action of selenium. While this vitamin has no direct effect on breast cancer, it can prevent the progress of mammary dysplasia, a precancerous condition of breast disease, to full-blown cancer. A dosage of 600 international units per day is adequate, along with daily doses of 150 micrograms (but no more) of selenium and approximately 1,000 milligrams of any magnesium supplement.
  • Breast tissue is especially vulnerable to damage from the carcinogens in tobacco smoke at two points in a woman's life, during puberty and during pregnancy, when breast cells are actively dividing. Secondhand smoke exposure during these times increases the risk of cancer.
  • Surveys have found that while nearly 25 percent of women perform breast self-examination seldom or never at all, as many as 18 percent examine their breasts daily or more often. Ironically, excessive self-examination also can interfere with effective treatment, since doctors making diagnostic decisions on the basis of these exams tend to falsely identify growths as cancer. If you are sufficiently concerned about breast health to make a daily exam, see a doctor for a complete workup.
  • Do not take supplements containing iron. Iron may be used by tumors to promote growth.
  • Folic acid has no effect on breast cancer in women who do not drink, but protects against breast cancer in women who drink more than 15 grams of alcohol (the equivalent of two to three drinks) per day. Doctors writing in the Journal of the American Medical Association recommend taking at least 300 micrograms of folic acid daily.
  • Estrogen replacement therapy may increase the risk of breast cancer in women who have never had breast cancer before.
  • If you experience itching, redness, and soreness of the nipples, especially if you are not currently breast-feeding a baby, seek evaluation by a physician. These can be symptoms of Paget's disease, a form of breast cancer.
  • Frequent exposure to medical x-rays has been linked to an increased risk of breast cancer.
  • Early or prolonged use of permanent dark hair dyes have been linked to breast cancer.
  • The stress of being diagnosed and treated for breast cancer in itself weakens the immune system. Psychological stress diminishes the capacity of natural killer (NK) and T cells to fight infection both during and after treatment for cancer. For this reason, stress management is extremely important to recovery.
  • Lymphedema is a swelling of the tissues that may follow cancer surgery.

More useful herbs

Breast cancer in men

Breast cancer strikes men only 1 percent as often as it strikes women. Because it is not often suspected as a cause of symptoms, it is often discovered at an advanced stage. Risk factors for breast cancer in men include diseases in which the body produces too much estrogen, family history, radiation exposure, and exposure to the tropical disease organism Schistosoma. In general, the same treatments are used for men as for women, except that in men spread of the disease may be treated by removal of the testes to eliminate the hormones that stimulate cancer growth.

Men who have breast cancer should consult with their physicians about the advisability of the herbs or formulas recommended for women to reduce estrogen production. Both men and women who have been exposed to the tropical disease schistosomiasis may benefit from the use of agrimony, as this disease can contribute to the development of both breast tumors and benign calcified cysts that appear as cancers on mammograms. Agrimony contains compounds that interrupt the life cycle of the parasite. It also stimulates B cells, immune-system cells that produce antibodies against cancer and various forms of infection. Take 1 cup of agrimony tea two to three times daily for up to three months.

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