Phytoestrogens are basically compounds derived from plants and possess actions that are comparable to that of estrogen - the most important sex hormone present in the body of the females. Phytoestrogens may be classified into two key clusters - isoflavones, which are present in red clover, soybeans, kudzu root and many others; and lignans, which are present in whole grains, flaxseed and a number of vegetables and fruits. It may be noted here that soy is an exceptional dietary resource of the extensively researched isoflavones known as daidzein and genistein.
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It is believed that as far as estrogen receptors found in cells are concerned, phytoestrogens may contend with the natural estrogens. By means of attaching to these receptors, phytoestrogens are able to avoid estrogen from invigorating specific tissues and hypothetically lessen the chances of having cancers, which are stimulated by estrogen. In effect, isoflavones are further powerful compared to lignans as far as interrelating with the estrogen receptors on cells in the body are concerned.
While phytoestrogens contend for the similar binding locations on the cells, they actually do not work in the same manner as the natural estrogens. For instance, chemically, isoflavones are just approximately 1/1000 as powerful compared to natural estrogens. However, in a number of the tissues in our body, phytoestrogens imitate the exploits of estrogen and may possibly ease the symptoms of menopause in the case of aged women. In other different tissues, the phytoestrogens obstruct the activities of estrogen and, in doing so, diminish the chances of developing a number of types of cancer, particularly breast cancer.
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Phytoestrogens may work within the body in several dissimilar manners. It may be noted that the chemical formation of phytoestrogens is akin to that of estrogen, and they may function in the form of copies or mimics of estrogen. In contrast, the effects of phytoestrogens are dissimilar from that of natural estrogen.
Functioning in the form of estrogen copies, phytoestrogens may possible have consequences similar to those of natural estrogen or impeded the effects of estrogen. In fact, the type of effect phytoestrogens will bring about is conditional of the dose of this compound derived from plants. When taken in lower doses, phytoestrogens may work similar to estrogen. However, when they are taken in higher doses, their function reverses and they actually obstruct the effects of natural estrogen. Precisely speaking, estrogen actually stimulates an entire protein family called estrogen receptors. Findings of latest researches have demonstrated that phytoestrogens additionally act together with a number of members belonging to the family of estrogen receptors. Nevertheless, it is believed that additional information is required regarding the manner in which the estrogen receptors function, particularly in the case of breast cancer. To conclude this issue, phytoestrogens that work in the form of estrogen copies or mimics have the potential to have an effect on the manufacture and/ or breaking down of natural estrogen by the body, in addition to the intensity of estrogen transported in the bloodstream.
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Phytoestrogens have the potential to have an effect on the communiqué channels between the cells, avoid the development of blood vessels into tumours or even modify the processes concerned in the progression of the DNA for multiplication of cells. However, it is still uncertain as to which of the effects mentioned here really occur. It is extremely likely that in excess of one of these processes may perhaps be functional. In addition, the consequences in different parts of the body may also be dissimilar.
Population studies undertaken by scientists have revealed a connection between diets that are rich in soy content and diminished risk of developing breast as well as endometrial cancer in women, in addition to prostate cancer in men. The finding of the study that has drawn maximum notice is the part where it compares the risks of developing breast cancer by Asian and American women. The research found that Asian women who consume a conventional diet containing plenty of soy actually face a much less risk of developing breast cancer compared to the American women. Besides breast cancer, the Asian women also seldom endure hot flashes and other symptoms of menopause. In fact, the phytoestrogens present in soy are said to be responsible for such protective results. Numerous controlled researches have discovered that administering diets that are supplemented with soy or those supplemented with isoflavones obtained from red clover leads to a diminished incidences of hot flashes endured by women in their menopausal stage.
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Laboratory tests as well as those conducted on animals demonstrate that phytoestrogens have the potential to slow down the growth of tumours. Examinations using cultured human breast cancer cells, prostrate cancer cells and leukemia cells have also shown that phytoestrogens can inhibit tumour growth.
Studies have also demonstrated that phytoestrogens possess the ability to slow down the oxidation process of the LDL (low-density lipoprotein) cholesterol or the 'bad cholesterol' - a step that is considered to stimulate the development of fatty plaque in the arteries. People who are experts in soy products are of the view that phytoestrogens are partially accountable for the cholesterol lowering consequences that are seen in the case of soy protein. Findings of several researches have also discovered that isoflavone supplements that are derived from red clover augmented the capability of arteries to extend and enable the blood to circulate freely - a task known as arterial acquiescence - seen in post-menopausal women.
A number of researches have also hinted that phytoestrogens may possibly facilitate in preventing osteoporosis. For instance, population studies undertaken at different times suggest that phytoestrogens are likely to work as protection against bone loss in elderly women, counting women whose diets offer below the recommended quantities of calcium. For example, Asian women drink very little amount of milk and milk products, and they also have a propensity to be slender and small-boned - features that would hypothetically augment their chances of developing osteoporosis. All these notwithstanding, the cases of osteoporosis among Asian women are slightly less compared to the American women. It is another issue that generally the Americans intake more amounts of calcium compared to the Asians. The diet of the Asians is rich in soy content and this is responsible for the diminished risks of developing osteoporosis.
Phytoestrogens are naturally present in legumes, soy, flaxseed, whole grains, vegetable, fruits, in addition to red clover. In fact, soy protein as well as soy foods, such as, roasted soybeans, tofu and soy milk are particularly excellent sources of phytoestrogens. You may buy isoflavone supplements obtained from soy or red clover in capsule or pill form. Several types of phytoestrogen supplementation available in the stores selling health foods enclose a blend of extracts of wild yam, isoflavones, and kudzu root plus dong quai - the herbal supplies of phytoestrogens - together with an assortment of vitamins as well as minerals. On the other hand, soy protein is sold in its powdered form that can be blended either with milk or juice.
The suggested dosage of isoflavones differs significantly, however, several experts mention about the average intake by Asians to approximately 25 mg to 50 mg every day as a harmless and probably effectual dose. Nevertheless, a number of highly powerful phytoestrogen supplements supply elevated doses of isoflavones, to the extent of 500 mg or even more.
A number of experts are actually worried that ingesting phytoestrogens in elevated doses is likely to boomerang by augmenting the chances of developing some types of cancer. According to them, post-menopausal women having undiagnosed breast cancer dependent on estrogen is one group of people who might be facing greater risks. Majority of the experts are of the view that for most people, counting males, it is generally safe to take a dose of 50 mg phytoestrogens on a daily basis. However, it is yet to be ascertained whether taking elevated doses of phytoestrogens regularly can result in any type of health problem.
Therefore, it is advisable that you exercise precaution while using phytoestrogen supplementations in which the levels of phytoestrogen may exceed that in other foods. As phytoestrogens have the ability to produce results akin to normal estrogen in humans, using them in the form of supplements for a prolonged period may possibly augment the chances of developing breast cancer. However, consumption of foods containing high levels of phytoestrogens in moderation is not likely to result in any adverse side effects and generally such foods are healthy for the body.
